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Top Systems Engineer Jobs in San Francisco, CA

Reposted 8 Days AgoSaved
Easy Apply
Remote or Hybrid
San Francisco Bay Area, CA
Easy Apply
180K-320K Annually
Senior level
180K-320K Annually
Senior level
Big Data • Information Technology • Software • Database • Analytics
Develop and optimize distributed systems for syncing customer data, focus on scalability, reliability, and performance for global clients.
Top Skills: CachingData StreamingDistributed SystemsMulti-CloudMulti-RegionPerformance OptimizationReal-Time Systems
8 Days AgoSaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Information Technology
As a Senior Systems Engineer, you'll improve AWS infrastructure, utilize infrastructure-as-code, implement observability, and ensure security in production environments.
Top Skills: AlbAnsibleAsgAWSCi/CdCloudwatchDatadogDockerEc2EcsElbGithub ActionsIamNomadOpentelemetrySecrets ManagerTerraformVpc
18 Days AgoSaved
In-Office
San Francisco Bay Area, CA
170K-210K Annually
Mid level
170K-210K Annually
Mid level
Aerospace • Hardware • Logistics • Robotics • Software • Transportation
The role involves developing critical software for a real-time autonomous delivery network, focusing on fleet operations, orchestration, maintenance, and simulation systems while ensuring reliability and operability in high-stakes environments.
Top Skills: AISoftware Engineering
9 Days AgoSaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Software • Virtual Reality • Analytics
This role manages day-to-day operations of Azure and server infrastructures, focusing on stability, cost management, and security while addressing complex incidents and automation of workflows.
Top Skills: AzureItilLinuxPowershellVMwareWindows Server
Reposted 18 Days AgoSaved
Hybrid
San Francisco Bay Area, CA
195K-264K Annually
Senior level
195K-264K Annually
Senior level
Information Technology • Internet of Things
The Senior Machine Learning Engineer will design and implement ML systems, optimize data pipelines, and collaborate on ML workflows for personal injury legal solutions.
Top Skills: APIsDistributed ComputingGenerative AiMachine LearningNatural Language ProcessingPythonVector Databases
Reposted 18 Days AgoSaved
In-Office
San Francisco Bay Area, CA
180K-250K Annually
Senior level
180K-250K Annually
Senior level
Aerospace • Hardware • Logistics • Robotics • Software • Transportation
The Staff Systems Engineer focuses on deploying high-reliability autonomous systems in safety-critical environments, defining safety requirements, and ensuring robust system performance.
Top Skills: Autonomous SystemsElectromechanical SystemsStatistical AnalysisSystems Modeling
Reposted 18 Days AgoSaved
In-Office
San Francisco Bay Area, CA
118K-153K Annually
Senior level
118K-153K Annually
Senior level
Biotech
Design, develop, and support full-stack web applications that enable data workflows, logistics, scientific processes, and advanced analytics. Provide troubleshooting, application support, configuration, testing, documentation, and user training. Collaborate with scientists, business, and IT partners to enhance applications, improve efficiency, and meet project deadlines while working autonomously in Agile environments.
Top Skills: C#ReactSQL
Reposted 9 Days AgoSaved
Easy Apply
Remote
San Francisco Bay Area, CA
Easy Apply
95K-105K Annually
Senior level
95K-105K Annually
Senior level
Biotech
The Quality Engineer, Systems & Compliance role involves managing GxP system compliance, vendor qualification, audit readiness, and developing validation plans to ensure regulatory adherence.
Top Skills: Alcoa+ Data IntegrityEqmsEtmf System QualificationFda Quality Management System RegulationGamp 5Greenlight GuruGxp SystemsIso 13485:2016MastercontrolQualioVeeva Vault Qms
Reposted 9 Days AgoSaved
Remote
San Francisco Bay Area, CA
200K-316K Annually
Senior level
200K-316K Annually
Senior level
Cloud • Security • Software • Generative AI
The role involves enhancing Elasticsearch's performance in distributed systems, managing cluster coordination, debugging complex systems, and leading cross-team projects.
Top Skills: ElasticsearchJavaLuceneNetty
Reposted 9 Days AgoSaved
Remote
San Francisco Bay Area, CA
200K-316K Annually
Senior level
200K-316K Annually
Senior level
Cloud • Security • Software • Generative AI
The Principal Software Engineer I will enhance Elasticsearch components for performance, manage cluster coordination, and debug complex distributed systems while leading projects.
Top Skills: ElasticsearchJavaLuceneNetty
10 Days AgoSaved
Remote
San Francisco Bay Area, CA
115K-120K Annually
Junior
115K-120K Annually
Junior
Information Technology • Consulting
Responsible for maintaining and enforcing automation system standards and conducting audits. Collaborates with teams to ensure compliance with security and regulatory requirements.
Top Skills: ClickupGitIgnitionMS OfficeMs SharepointPlcScada
Reposted 19 Days AgoSaved
In-Office
San Francisco Bay Area, CA
230K-385K Annually
Mid level
230K-385K Annually
Mid level
Artificial Intelligence • Machine Learning • Generative AI
Design and scale infrastructure for multimodal training at OpenAI, focusing on distributed data systems and collaborating with researchers.
Top Skills: Data OrchestrationDistributed StorageDistributed SystemsMachine Learning InfrastructureStreaming Infrastructure
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Reposted 19 Days AgoSaved
In-Office
San Francisco Bay Area, CA
100K-100K Annually
Mid level
100K-100K Annually
Mid level
Information Technology • Software
As a Systems Engineer, you will develop core systems for processing unstructured data, ensuring speed, resilience, and security in mission-critical workflows.
Top Skills: C++Rust
Reposted 19 Days AgoSaved
Easy Apply
In-Office
San Francisco Bay Area, CA
Easy Apply
180K-250K Annually
Mid level
180K-250K Annually
Mid level
Cloud • Digital Media • Information Technology
Design and implement model serving architectures, develop monitoring tools, and optimize performance for generative media models working with Applied ML teams.
Top Skills: NsightPyTorchTensorrtTransformerengineTriton
Reposted 19 Days AgoSaved
In-Office
San Francisco Bay Area, CA
180K-240K Annually
Senior level
180K-240K Annually
Senior level
Machine Learning • Generative AI
The AI Field Engineer will drive technical sales success by partnering with sales teams, designing solutions, conducting demos, and addressing customer needs in AI/ML infrastructure.
Top Skills: AWSAzureCloudFormationDockerGCPKubernetesPulumiTerraform
Reposted 19 Days AgoSaved
Hybrid
San Francisco Bay Area, CA
187K-225K Annually
Senior level
187K-225K Annually
Senior level
Artificial Intelligence • Machine Learning • Robotics • Software • Transportation • Design • Manufacturing
Lead reliability engineering for EV powertrain systems (EDU, high-voltage battery, power distribution). Define reliability targets, drive DFMEA, develop virtual and physical validation and PHM strategies, support field monitoring and corrective actions, embed durability in system design, and collaborate with suppliers and cross-functional teams to improve lifecycle reliability.
Top Skills: PysparkPythonSQL
10 Days AgoSaved
Remote
San Francisco Bay Area, CA
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Artificial Intelligence • Big Data • Software • Infrastructure as a Service (IaaS)
As a Senior Systems Engineer, you'll design high-performance data management systems, optimize for scalability, solve distributed challenges, and collaborate with the team to maintain code quality. Requires strong backend development and systems programming expertise, particularly in Rust.
Top Skills: C/C++Change Data CaptureFlinkGoGrpcKafkaRustTcp/Ip
10 Days AgoSaved
Remote
San Francisco Bay Area, CA
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Artificial Intelligence • Big Data • Software • Infrastructure as a Service (IaaS)
The Senior Systems Engineer will architect and implement high-performance data plane components, optimize systems for scale, and lead initiatives in distributed systems. Responsibilities include writing production-grade code, mentoring team members, and communicating technical decisions effectively.
Top Skills: CC++FlinkGoGrpcKafkaRustTcp/Ip
10 Days AgoSaved
Remote
San Francisco Bay Area, CA
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Artificial Intelligence • Big Data • Software • Infrastructure as a Service (IaaS)
As a Senior Systems Engineer, you'll architect and implement high-performance components for data and control planes, optimize systems for scale, solve distributed problems, ensure code correctness, and collaborate with peers.
Top Skills: C/C++FlinkGoGrpcKafkaRustTcp/Ip
10 Days AgoSaved
Remote
San Francisco Bay Area, CA
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Artificial Intelligence • Big Data • Software • Infrastructure as a Service (IaaS)
Design and implement high-performance components for data and control planes, optimizing systems for scale, and ensuring correctness in code. Mentor and collaborate with the team on technical design and code reviews.
Top Skills: C/C++FlinkGoGrpcKafkaRustTcp/Ip
10 Days AgoSaved
Remote
San Francisco Bay Area, CA
250K-413K Annually
Senior level
250K-413K Annually
Senior level
News + Entertainment
The Software Engineer will design and develop internal solutions enhancing employee productivity, collaborating across teams to create scalable applications and integrating advanced technologies like AI.
Top Skills: GraphQLNode.jsPythonReactRest
Reposted 10 Days AgoSaved
In-Office or Remote
San Francisco Bay Area, CA
113K-143K Annually
Senior level
113K-143K Annually
Senior level
Insurance • Software
Lead the design, implementation, and optimization of IT systems while ensuring performance, security, scalability, and mentoring junior engineers.
Top Skills: AclsAnsibleBashCronDockerEncryptionFirewallsGitKubernetesLinuxMfaOpenshiftPodmanPowershellPrometheusPythonRdpSolarwindsSshVMwareWindows ServerZena
Reposted 10 Days AgoSaved
Easy Apply
Remote
San Francisco Bay Area, CA
Easy Apply
Expert/Leader
Expert/Leader
Healthtech • Software • Database • Biotech • Pharmaceutical
As a Principal Engineer for AI Systems, you will lead AI implementation and integration across the organization, ensuring compliance, enhancing workflows, and managing AI technology platforms while collaborating with various teams to drive efficiency and support AI adoption.
Top Skills: AnthropicAPIsAWSAzureChatgptClaudeMakeMlopsOpenaiPythonZapier
Reposted 20 Days AgoSaved
In-Office
San Francisco Bay Area, CA
150K-240K Annually
Mid level
150K-240K Annually
Mid level
Artificial Intelligence • Information Technology • Software
The Founding Engineer will design and implement ML platforms and tools, creating APIs and SDKs, while also improving customer workflows and experiences.
Top Skills: AWSDockerKubernetesLinuxPython
Reposted 20 Days AgoSaved
Hybrid
San Francisco Bay Area, CA
165K-330K Annually
Mid level
165K-330K Annually
Mid level
Software
Design and implement RDMA/InfiniBand networking primitives for distributed GPU inference, optimize communication for Disaggregated KV Cache and WideEP, enable sub-10s model startup, validate hardware performance on H100/H200/B200/B300/GB300 clusters, build observability tools, and optimize or author communication kernels (NCCL/NVSHMEM/UCX).
Top Skills: 3FsC++Gpudirect Storage (Gds)InfinibandNcclNvlinkNvshmemPythonRdmaRoce V2SglangTcp/IpTensorrt-LlmUcxVllmWeka
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